CRISPR preprints

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Theme editors: Chunjie Liu


Preprint Authors Date Reviews & Comments Intersect Actions
In Troyer Syndrome Spartin loss induces Complex I impairments and alters pyruvate metabolism 7th Dec 2018
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CCN4 shifts melanoma cells from a fragile proliferative state to a resilient metastatic state 7th Dec 2018
melanoma Bookmark
Lessening of porcine epidemic diarrhoea virus susceptibility in piglets after editing of the CMP-N-glycolylneuraminic acid hydroxylase gene with CRISPR/Cas9 to nullify N-glycolylneuraminic acid expression 6th Dec 2018
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Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition 6th Dec 2018
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CRISPR spacers indicate preferential matching of specific virioplankton genes 6th Dec 2018
metagenomics natural_selection Bookmark
Why Put-Up with Immunity when there is Resistance: An Excursion into the Population and Evolutionary Dynamics of Restriction-Modification and CRISPR-Cas 6th Dec 2018
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Double Stranded DNA Damage and Genome Editing Trigger Ribosome Remodeling and Translational Shutdown 5th Dec 2018
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Strong gene activation with genome-wide specificity using a new orthogonal CRISPR/Cas9-based Programmable Transcriptional Activator. 5th Dec 2018
rnaseq Bookmark
Cas4 nucleases can effect specific integration of CRISPR spacers 5th Dec 2018
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Epigenetic derepression of FKBP5 by aging and stress contributes to NF-kB-driven inflammation and cardiovascular risk 4th Dec 2018
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GRIBCG: A software for selection of sgRNAs in the design of balancer chromosomes 3rd Dec 2018
recombination Bookmark
MAU2 and NIPBL variants in Cornelia de Lange syndrome reveal MAU2-independent loading of cohesin and uncover a protective mechanism against early truncating mutations in NIPBL 3rd Dec 2018
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Optimised CRISPR-Cas9 mediated single molecule imaging for accurate quantification through endogenous expression. 1st Dec 2018
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Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors 30th Nov 2018
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Ribozyme-Mediated, Multiplex CRISPR Gene Editing and CRISPRi in Plasmodium yoelii 30th Nov 2018
malaria Bookmark
The Drosophila fussel gene is required for bitter gustatory neuron differentiation acting within an Rpd3 dependent chromatin modifying complex 30th Nov 2018
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Massively parallel profiling and predictive modeling of the outcomes of CRISPR/Cas9-mediated double-strand break repair 29th Nov 2018
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Behavioral changes and growth deficits in a CRISPR engineered mouse model of the schizophrenia-associated 3q29 deletion 29th Nov 2018
neurodevelopmental_disorders schizophrenia Bookmark
Base editing generates substantial off-target single nucleotide variants 28th Nov 2018
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BAPC-assisted CRISPR/Cas9 System: Targeted Delivery into Adult Ovaries for Heritable Germline Gene Editing (Arthropoda: Hemiptera) 28th Nov 2018
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