Completed on 7 Mar 2016 by Christophe Dessimoz.
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My authors have satisfactorily addressed my remarks. I only have two small comments on the new analyses:
1) The comparison with other clustering methods is good addition. The fragility of hierarchical methods and "partitioning around medoid" with respect to missing data is surprising. The authors should make data and scripts available.
2) The legend of new figures 3 and 4 should be clearer. As it stands, one needs to read the main text to understand that "zero, ten, twenty" refers to percentages of missing data.
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Authors' response to reviews: (https://static-content.springer.com/openpeerreview/art%3A10.1186%2Fs13742-016-0152-3/13742_2016_152_AuthorComment_V2.pdf)